Introduction to Stereochemistry via Augmented Reality (StereoChem)


Purpose of using StereoChem

StereoChem is an Augmented Reality based mobile app, that allows learners to spatially visualize and interact with 3D molecular models. Visualization and interaction with molecules happens within the real space of the learners in relation to the objects lying around them. This offers enhanced spatial perception to the learner regarding the spatial orientation of atoms or groups of atoms in a molecule. This is critical in the learning of Stereochemistry, where just the difference in the spatial orientation of stereo chemicals gives rise to different physical, chemical or biological properties.


Learning Stereochemistry using Augmented Reality 3D Molecular Visualization




Project Team:


  • Narasimha Swamy
  • Pankaj Chavan
  • Siddhesh Walunj


Resources required

  • StereoChem: StereoChem is an android app built using Unity 3D and open source molecular viewer called Jmol

  • Read Me

Getting started with StereoChem

  • If you wish to use the StereoChem then download the app from the link given below. Then install the app in your android mobile. Also get the print out of the marker images provided in another link. Now you can start scanning the marker images using StereoChem to visualize and interact with the augmented reality 3D molecules.
Download ZIP
  • If you wish to use StereoChem online, without downloading the software, then click on:
    • Teacher's corner: If you are a teacher.
    • Researcher's corner: If you are a researcher.
    • Developer's corner: If you are a developer.

Teacher's corner

Introduction

In Stereochemistry, diagrammatic representation of 3D molecular structures into 2D symbolic diagrams poses immense challenge to the learners because those 2D symbolic diagrams should also communicate spatial orientation of atoms or groups of atoms in the stereoisomers. Adding to this complexity, Stereoisomerism relationship is represented by many different 2D conventions called Wedge and Dash, Newman, Cram and Fischer projections for different groups of stereoisomers. Current desktop based molecular visualization applications are limited in terms of the richness of spatial perception they offer for interpreting stereoisomers. StereoChem app on the other hand renders 3D molecular visualizations to learners in their actual space in relation to the things lying around them. This increases the spatial perception of learners towards the different spatial orientation of atoms in the molecules.



Activity 1: Identifying and distinguishing stereoisomers Teacher Manual
Activity 2: Identifying pairs of enantiomers and diastereomers Teacher Manual

Researcher's corner

Research work done with StereoChem

Cite as: Swamy, N. Chavan, P. S. & Murthy, S. (2018), StereoChem: Augmented Reality 3D Molecular Model Visualization App for Teaching and Learning Stereochemistry, IEEE International Conference on Advanced Learning Technologies.

Abstract: Understanding Stereochemistry is of critical importance for students aiming to be future chemists, molecular biologists, pharmacists, pharmacologists or physicians. Stereochemistry focuses on the study of the stereoisomers which have the same molecular formula but differ only in the spatial orientation of their atoms resulting in different physical, chemical or biological properties. Hence spatial thinking skill is essential for students to interpret stereoisomers. Augmented reality helps enhance the spatial perception of 3D molecules.
StereoChem, our mobile app for visualizing augmented 3D molecular models harnesses this advantage of augmented reality to aid teaching and learning of Stereochemistry. This paper gives a brief introduction to the significance and challenges of learning Stereochemistry. It describes the design inputs that we considered for encouraging the ubiquitous use of our app by chemistry teachers and students, then discusses the development of the StereoChem app and the teaching-learning contexts in which it can be used. Finally, it gives an account of the user experience study done with 50 chemistry teachers.


Future work:
The project is closed now but you can explore the following areas:
  • 3D Property:
  • Current research has only dealt with the evaluation of the feasibility and the appropriateness of the StereoChem app for learning the nuances of 2D structural representations of stereo chemicals by visualizing 3D molecules. And also the current visualizations of 3D molecules in StereoChem are of static nature. Further research can examine the scope for incorporating dynamic models of molecules. Dynamic models of augmented reality molecules widens the scope of StereoChem app for learning diverse concepts in chemistry. It can then be used to learn the molecular mechanism of chemical reactions, self assembly of molecules, the interaction of light with molecules and many others.
  • Student engagement:
  • Current research conducted a pilot user experience study with both students and teachers. Further research can look into the differences in the engagement when students are performing learning activities using desktop based visualization of molecular models with that of ones visualized using StereoChem.
  • Teacher Use of StereoChem in Classroom:
  • Study of teacher use of StereoChem in classroom would offer deeper insights into the constraints of StereoChem in the classroom setting. This would provide potential directions for its refinement and further improvement.

    Developer's corner

    Introduction:
    StereoChem is an android mobile app developed using Unity 3D game engine and the Vuforia SDK platform. It gets its 3D molecules from the open source molecular viewer called Jmol. An advantages of using Jmol is that it acts as a platform for molecular editing. We can get the required molecule in Jmol and then edit it to add features like highlighting specific atoms by coloring, drawing axes or planes across atoms in a molecule before importing it into Unity 3D game engine This work is licensed under a Creative Commons Attribution 4.0 International License. Creative Commons Licence
    Resources Required:
    Git Hub link: https://github.com/nexteducationrlab/steriochem Read Me
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